Those Who Transcend the Known

Those Who Transcend the Known

Those Who Transcend the Known

The best part of my career has been meeting eminent people and learning—often quietly—about the many facets of human excellencesomething missed by those who pursue excellence in their own fields and live within their silos and echo chambers. Even now, when I travel less, Providence seems to arrange moments of rare grace: encounters with individuals whose mere presence teaches. In the presence of such people, I feel a calm, reassuring force—an affirmationthat human life, at its highest, is about the expansion of consciousness. It is about helping the mind escape the cage of instinct, habit and conditioning, and align itself with what is good beyond personal or immediate interesttowards the greater good of others.

It was in this spirit that I attended the Global Head & Neck Precision Onco Summit 2026 at Yashoda Hospitals, Hyderabad, to which I was invited by Dr. S. Chinnababu, with whom I co-authored a book on cancer, Live for a Legacy, in 2023; it has recently been revised and republished in a newedition. I listened to the inaugural keynote by the globally renowned head and neck surgical oncologist Dr. Anil K. D’Cruz, and within minutes, it was evident that this was neither a performance nor an exercise in persuasion. It was the voice of a man who has spent a lifetime standing at the frontier of uncertainty—where decisions are irreversible, margins are narrow, and humility is not merely a personal virtue—it is an ethical requirement of the profession.

Dr. D’Cruz’s presence is strikingcomposed, precise and unsentimental. There was no sugar-coating. This is what surgery can do, he seemed to say. ‘Beyond this lies adventurism. What gave these words their uncommon force was the audience before him—the very best in the field, clinicians and scientists who themselves work at the frontiers of knowledge. Yet the hall was held in attentive silence. The profundity of his words was both compelling and commanding, for they arose from strength, not hesitation. Even as a lay observer, the ethical clarity was unmistakable. Each tumour is biologically unique; each patient carries a different physiology, psychology and social context. Wise care in head and neck oncology, therefore, demands strength of judgement—an intelligent, patient-specific integration of surgery, radiation and systemic therapy, increasingly informed by molecular profiling and immuno-oncology, and anchored in the courage to respect limits. Doctors are mere professionals in their chosen field; they are not gods.

The field itself has transformed profoundly. High-resolution imaging, PET-CT fusion and intra-operative navigation have refined precision. Microvascular reconstruction restores not just anatomy but speech and swallowing. Intensity-Modulated Radiation Therapy (IMRT) and image-guided radiotherapy have reduced collateral damage. Checkpoint inhibitors targeting the transmembrane proteins programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1)have opened new options for treating recurrent and metastatic disease. Yet tools, however advanced, do not absolve us of responsibility. They extend capability; they do not replace wisdom. Without ethical restraint, technology risks becoming excessive.

This restraint is increasingly difficult in a system where medicine is no longer practised by independent agents. Every doctor is embedded in institutions—hospitals, insurers, diagnostics, and supply chains—that shape incentives and choices. Excellence today requires not only skill but resistance to the gravitational pull of profit and spectacle. It requires an elevation of consciousness commensurate with capability.

I sat with Dr. D’Cruz as co-chair during Dr. Chinnababu’spresentation on cancer prevention by traversing the last mileaway from cities, into villages and hutments, where marginalised, poor and tribal communities live. Through the Grace Cancer Foundation, a creation of his own, Dr.Chinnababu has spent over a decade raising awareness and promoting early referral. The science here is disarmingly simple: when detected early, most cancers are curable with modest intervention; when detected late, treatment becomes prolonged, costly and uncertain. Prevention and early diagnosis lack glamour. They demand patience, logistics, trust and relentless follow-up—where conscience meets competence. And there is no money in it.

As I stood between Dr. D’Cruz and Dr. Chinnababu, I felt adéjà vuan unmistakable sensation I had experienced many times before in the company of Dr. A. P. J. Abdul Kalam. Dr.Kalam is no longer with us physically, yet some individuals never truly depart. Their way of being—how they listen, decide, pause and act—never goes away, and lives as an imprint so deep that it reappears when the conditions are right. What I felt in that moment was not nostalgia or memory. It was recognition—an experiential truth that needs no explanation, only attentiveness.

Dr. D’Cruz’s own journey exemplifies a life devoted to knowing what is not yet known. Educated at St. John’s Medical College, Bengaluru, trained in surgery at the University of Mumbai, and forged over 38 years at Tata Memorial Hospital—including 28 as Professor and Head—he has helped define standards of care respected worldwide. Since 2019, as Director of Oncology at Apollo Hospitals, he has shown that disciplined excellence and large systems need not be incompatible. His legacy lies not only in surgeries and publications, but in generations trained to think before they cut, to ponder before they decide, and to respect biology over ego.

Watching Dr. D’Cruz draw firm ethical boundaries around intervention, and Dr. Chinnababu persistently widen the circle of care to include those whom systems routinely forget, I sensed the same inner alignment I had witnessed years earlier. It was the lived coherence between thought and action, between capability and responsibility. Such moments reveal themselves not through argument or ideology, but through experience—and it is from this realm of lived experience that thinkers like Sri Aurobindo spoke of a higher order of consciousness made visible in ordinary human work.

These are the people Sri Aurobindo described in The Life Divine—not saints withdrawn from the world, but individuals fully embodied in work, inwardly governed by something larger than ambition or fear. Such people do not announce their spirituality. They live it through precision, discipline and care. In medicine, this quality is unmistakable: the courage to say no when intervention will harm; the choice of prevention over spectacle; the building of institutions rather than empires; the teaching of when not to act.

Sri Aurobindo argued that human evolution is ethical and conscious, not merely technological. The next step would be taken by individuals who master inner compulsions while remaining fully engaged with the world. At the Summit, I saw this principle enacted—quietly—by a master surgeon who knows his limits and a public-health clinician who refuses to abandon the poor.

This is not hero-worship. It is pattern recognition. In a time when medicine risks becoming algorithm-driven or profit-maximised, such lives are living correctives. They remind us that advanced tools—robotics, precision radiotherapy, immunotherapy and AI-guided diagnostics—are morally neutral until guided by consciousness.

Dr. Kalam once told me that the true test of a professional life is whether one leaves behind clarity rather than confusion. As I left the hall, that clarity lingered. It reaffirmed a belief I have long held: humanity reaches its highest expression not in dominance, but in service guided by knowledge and humility. These are the ones who transcend the known—and, in doing so, lift us with them.

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The Alchemy of the Balcony

The Alchemy of the Balcony

The Alchemy of the Balcony

I have been deeply engrossed in reading Shakespeare for a while. It remains one of the most astonishing paradoxes in literary history that Romeo and Juliet—a drama pulsing with murder, deception, impulsive rebellion and ethical transgression—has been remembered across continents and centuries, not for its violence but for a single, moonlit balcony. A recent film, O’Romeo, brought this truth to light by focusing on a passionate, high-stakes romance that mirrorsthe central, tumultuous love story of the classic play. Similar to the Montague/Capulet feud, O’Romeo roots in an intense rivalry within the modern-day Mumbai underworld, and though it does not replicate scenes, it clinically examines the perils of forbidden love.

Read plainly, the narrative is chaotic, almost startling in its speed and recklessness. A street brawl erupts within the first hundred lines. Romeo broods over a different girl altogether. Juliet, scarcely fourteen, is pressured into a marriage she does not want. Romeo trespasses into her home under the cover of night. Mercutio is slain in broad daylight, Tybalt falls in vengeance, Paris dies at the tomb, and Friar Lawrence—custodian of spiritual wisdom—concocts a dangerous sleep potion to fake Juliet’s deathso potent that he boasts it can borrow life from death. 

“And in this borrowed likeness of shrunk death” (Act 4, Scene 1)

Immediately after Romeo kills Tybalt, he realises that his impulsive act of revenge has made him a plaything of fate. He must go into exile to save his life. He laments, in a moment of bitter clarity,

 “O, I am fortune’s fool!” (Act 3, Scene 1)

Nothing about this world is calm or orderly; it is a society fermenting with feud, pride, honour and haste. Yet, despite this tumult, the moment that humanity has chosen to preserve, paint, film, dramatise and fall in love with is the quiet, tremulous exchange beneath Juliet’s window—the instant when Romeo whispers, breath held like a prayer, that it is the east, and that Juliet is the sun!

On that balcony, the world of Verona briefly dissolves (Act 2, Scene 2). No feud intrudes. No parent watches; no dagger glints. No banishment looms. No potion is brewed. Instead, the scene glows with the innocence of discovery, and the trembling honesty of two young souls speaking without armour. For those few minutes, we glimpse love unshadowed by consequence. It is the only time they are entirely themselves.

But, soft! What light through yonder window breaks?

It is the east, and Juliet is the sun.

 Why does the world cling to this scene and not the events that shape the tragedy? Why is the balcony the emblem of the play, the cultural shorthand for love itself? The answer lies inselective human memory and irresistible human longing. We do not hold on to the full truth of an experience; we distil it. We are alchemists before we are historians. Juliet, aware of the danger, whispers fearfully,

“If they do see thee, they will murder thee.

 Yet her voice softens almost instantly as love overwhelms caution. She confesses in lines that have outlived kingdoms,

 “My bounty is as boundless as the sea, my love as deep.”  

Romeo, overwhelmed by her radiance, declares his own daring ascent,

“With love’s light wings did I o’erperch these walls”

In a way, Romeo and Juliet resembles the production of alcohol from coarse, sticky molasses. The raw materials of the play—the feud, the bloodshed, the rash decisions, and the priest’s deception—are thick, turbulent and unrefined. They bubble and ferment with heat, anxiety and danger. But when distilled, when separated from the heaviness of their origin, what rises is clear, fragrant and intoxicating: the pure vapour of yearning. The balcony scene is this vapour. It is the spirit extracted from the chaosthe moment when the residue falls away, and only emotion remains.

 The balcony endures because it transforms private longing into a public symbol. Shakespeare, with remarkable psychological insight, understood that audiences crave a moment of sincerity amid chaos. The balcony becomes the boundary between childhood and adulthood, between safety and danger, between the earth and the sky. It is not just a window; it is a frontier where the ordinary world ends and a myth beginsand myths endure because they contain something we need. The fights, the murders, the terrible haste—these are the slow-moving elements. The gentle glow of the balcony is the concentrated spirit that the world chooses to drink.

But why did this particular play, among countless tragic romances, become the universal template? Part of its power lies in its treatment of love not as possession but as revelation. Romeo and Juliet’s passion is not engineered, planned, or socially advantageous; it erupts with the inevitability of a storm. This rawness makes it universally recognisable. Every culture has known the fever of first love—the sense that feelings define destiny and that the world cannot possibly understand the urgency burning within.

Another reason lies in how Shakespeare endows recklessnesswith rationality, transforming the volatility of young love into something that sounds almost inevitable. Adolescence is often dismissed as impulsive, emotional and irrational; yetShakespeare dignifies its wildness by offering a poetic logic to passion. When Juliet muses, 

“What’s in a name? That which we call a rose

By any other name would smell as sweet. 

She is not merely defying her family’s feud; she is articulating the mind’s attempt to make sense of overwhelming feelings. In her reasoning, love itself becomes a force beyond labels, tribes, or inherited hatred—a self-justifying truth, like the rose’s fragrance.

Shakespeare thus allows recklessness to masquerade as clarity, giving young passion the philosophical defence it otherwise lacks. The audience, hearing such lines, accepts the lovers’ hurried devotion not as folly but as a kind of intuitive wisdom. We choose enchantment over caution because Shakespeare makes the illusion feel like the more profoundtruth.

This is why the story adapts so easily across cultures. In India, it becomes the tale of lovers divided by caste or community; in America, by race or class; in the Middle East, by tribe; in Japan, by tradition; in Europe, by politics or religion. The lovers become universal avatars of forbidden desire. Every society discovers its own feud within the Capulet–Montague hostility. Shakespeare’s poetry becomes the vessel into which each culture pours its own history, wounds and longings.

 In the end, the world does not remember that they died; it remembers that they loved. And that is the alchemy of the balcony: the moment when two ordinary lives rose into myth, proving that even in a universe of chaos, a single instant of pure feeling can become eternal. Shakespeare’s play closes with the Prince’s grave, a chastening reminder—

“For never was a story of more woe

Than this of Juliet and her Romeo.” (Act 5, Scene 3) 

Yet even in that sorrow, the world chooses the radiance that came before it, for tragedy is merely the residue, while love is the distilled spirit that rises. And thus the alchemy is complete: from the ferment of violence and folly emerges one pure, enduring vapour—the balcony’s eternal light.

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A Scientist and a Gentleman

A Scientist and a Gentleman

In every civilisation, there are two measures of success. One is public and noisy—titles, awards, positions, headlines, and the temporary glow of importance. The other is almost invisible: the quality of a human being. History remembers the first for a moment and the second forever. The tragedy of modern life is that we have learned to celebrate achievers and forgotten how to recognise gentlemen.

Worldly success has a remarkably brief half-life. Today’s titan becomes tomorrow’s emeritus, gracefully presiding over empty ceremonies, applauded by people who no longer rely on him. His power has vanished; only his manners remain—if he ever had any. Yet manners, ethics and inner stature are exactly what determine whether a person’s life develops into dignity or withers into bitterness.

Hollywood once tried to explain this distinction in its own way. The 1982 film, An Officer and a Gentleman, tells the story of a man who earns his stripes not through privilege but through discipline, loyalty and inner transformation. The title itself suggests something profound: that rank alone does not make one worthy—character does. In real life, however, such gentlemen are not forged on parade grounds but in the quiet spaces where no one is watching.

I learned this not from philosophers but from a scientist.

My personal journey unfolded under the long, blessed shadow of Dr. A. P. J. Abdul Kalam. For thirty-three years, I followed that rare blend of visionary and ascetic, learning how greatness can coexist with humility. Under his watchful guidance, I developed from a mechanical engineer into a missile scientist—from working with titanium for high-pressure air bottles, to designing thick-walled magnesium control bays and aluminium-alloy airframes, wings and fins, and ultimately to handling delta-ferrite-free austenitic steels for coronary stents. These were not just material changes; they represented expansions of imagination. Dr. Kalam had a profound passion for civilian spin-offs of defence technology. To him, a missile was never merely a weapon—it was a bridge to healthcare, energy and national dignity.

Through him, I encountered many remarkable minds. Yet among them all, one distinguished himself—not because he was louder, but because he was quieter. That man is Dr. Chandrasekhar Srivari.

We often assume that great scientists must be socially distant, even emotionally detached. Their minds are so immersed in abstractions that ordinary human gestures seem trivial. Like deep-sea divers, they operate below the waves, unaffected by surface noise. I expected Dr. Chandrasekhar to be like that—brilliant but removed, organised like elements in a periodic table.

Instead, the first thing he did was walk to a small fridge in his office and fetch me a bottle of water himself when I visited him for the first time in his Director’s office at the Indian Institute of Chemical Technology in Hyderabad. He did not ring a bell. He did not summon an assistant. He stood up and served. That simple act changed everything.

In that moment, I realised that I was in the presence of a different species of greatness. Not the kind that feeds on hierarchy, but the kind that dissolves it. The gentleman is not someone who expects service; he is someone who offers it.

As our meetings grew more frequent, I came to recognise the scale of Dr. Chandrasekhar’s scientific work. His approach to organic synthesis—particularly of marine natural products—was distinguished by extraordinary originality. These compounds were not merely academic curiosities; they were potential life-saving solutions for the developing world, addressing diseases like tuberculosis and malaria that continue to afflict the poor long after the rich have found cures.

His development of polyethylene glycol (PEG) as a green solvent was a quiet revolution. PEG is non-toxic, biodegradable, inexpensive, recyclable, and has low vapour pressure. In an era when chemistry is under scrutiny for its ecological footprint, this was a profound contribution. It made high-end synthesis compatible with environmental ethics.

His total synthesis of Eribulin—one of the most complex anticancer drugs ever created—was a tour de force of human intellect. It has immense commercial and medical value. And yet, outside specialist circles, almost no one knows his name. When COVID-19 shook the world, he quietly delivered a crucial adjuvant for Covaxin, contributing to one of India’s proudest scientific responses. Again, no parade followed.

Who recognises the flour-mill worker? Only the chefs are celebrated. The world observes the meal, not the milling process. It applauds the performance, not the preparation. It reveres what is visible, not what is essential. This is where the significance of the gentleman becomes vital.

A gentleman is not defined by applause. He is defined by indifference to it. His self-worth is not tethered to public recognition but to private standards. He does not ask whether he is being noticed; he asks whether he is being useful.

When I once gently asked Dr. Chandrasekhar how he felt about his work not receiving wider acclaim, he smiled—not with resignation, but with freedom. That smile told me everything. He had already transcended the marketplace of vanity. He knew that history’s truest rewards are not medals but meanings.

The gentleman lives in alignment. His actions, values and intellect are not at war with one another. He does not need to shout because he has nothing to prove. He does not hoard power because he does not fear losing it. He does not exploit people because he does not measure life in terms of extraction.

Shakespeare understood this long before modern academia. In King Lear, when the king asks his daughters to declare their love, Goneril and Regan perform eloquently. Cordelia refuses spectacle:

“I cannot heave my heart into my mouth.

I love your Majesty according to my bond; no more nor less.”

In our age of relentless self-promotion, Cordelia’s restraint is revolutionary. Dr. Chandrasekhar Srivari’s life gives that truth a scientific form. In chiral chemistry, two molecules can be mirror images—identical in structure yet opposite in effect: one healing, the other harmful. He lives that lesson. His brilliance is tempered by humility, so that knowledge is transformed into grace.

A scientist and a gentleman—this is the highest calling. In a civilisation of movers and shakers chasing visibility as a form of immortality, Dr. Chandrasekhar remains a gentleman by choice. Science, at its highest, is not merely about discovery; it is about character. A scientist who lies, plagiarises, intimidates, or exploits may produce papers, but he can never produce trust. Dr. Chandrasekhar’s ethics are not added to his intellect; they are embedded in it.

Whenever I meet him, I feel the quiet presence of Dr. Kalam—of that rare fraternity for whom knowledge is never a ladder to climb, but a light to hold for others. In such men, science does not merely advance; it acquires a soul. And in their company, one is reminded that to be a great scientist is admirable, but to be a scientist and a gentleman is a form of grace.

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Learning the Art of Writing by Reading

Learning the Art of Writing by Reading

Learning the Art of Writing by Reading

I enjoy reading quite a lot—sometimes as much as ten hours a day, though on average about eight. Reading has become my primary pastime—not as a leisure activity, but as a discipline. I read good books, chosen carefully, ordered online and added to a personal library built slowly and meticulously over the past fifty years. Every book is wrapped in a transparent plastic cover to protect it from dust and decay. I write in the margins, underline passages and affix slips of paper with tape. Books, for me, are not objects to be preserved in pristine condition; they are working instruments. I converse with them.

After publishing thirty-five books, I have decided not to write any more in that form. The inspiration came from Shakespeare, who wrote nothing in his last six years. However, I continue to write blogs—shorter, more flexible, and closer to thought in motion. Since May 2019, these blogs have been curated by Tanya Seth-Reddy. There are now more than 160 of them, each roughly a thousand words, recording observations, reflections, and, most importantly, stories of extraordinary people I have encountered. Sakal Publications published a book titled Spectrum, drawn from 150 of these blogs, that presents both my worldview and my writing style.

According to an AI analysis of my blogs, my writing falls within the stream-of-consciousness tradition pioneered by James Joyce and Virginia Woolf. I accept that description with some hesitation, because style is not something one consciously adopts. It emerges from long exposure, absorption and imitation—often unconsciously. On my website, I list ten books that shaped my thinking and explain how each influenced me at a particular stage of life. I neither inherited writing nor was educated in literature, nor learned to write through workshops or manuals. I learned to write by reading.

Among all writers, V. S. Naipaul has influenced me most—his moral seriousness, his clarity and his refusal to sentimentalise. Among living authors, Kazuo Ishiguro, who won the Nobel Prize in 2017, has been a profound teacher. Never Let Me Go, and Klara and the Sun confront the future not with spectacle, but with restraint, presenting a quiet humanity staring down an ethically diminished world. Margaret Atwood, especially through her MaddAddam trilogy, is another great teacher. She does not predict the future; she extrapolates from the present. These writers show what it means to think through fiction.

Here, I want to explain precisely what I mean by learning to write by reading, using Oryx and Crake—the first book I read in 2026—as an example.

In Oryx and Crake, Oryx is presented less as an animal than as a sound—a mantra severed from its original referent. The word survives, but its source, the antelope, has faded away. In this detachment lies Atwood’s quiet warning: meanings once rooted in lived reality are now abstracted, commodified, and hollowed out. Oryx’s own life mirrors this condition. She is shaped by forces she neither names nor controls, carried along by systems that preserve surface appearances while draining experience of depth.

Crake, by contrast, takes his name from a marshland bird that feeds in shallow waters, surviving on insects and molluscs. It is a creature adapted to liminal terrain—neither land nor water, neither depth nor stability. Atwood invokes this image deliberately. The world of Oryx and Crake resembles a vast marshland: ethically shallow, ecologically fragile and technologically saturated. In this landscape, technology does not cultivate or sustain; it forages. It feeds on natural resources, on bodies, on attention, and ultimately, on the human mind itself. Together, Oryx and Crake name a present in which words drift free of meaning and intelligence thrives in shallow ground—efficient, adaptive and extractive, yet incapable of reverence or restraint.

Atwood sets her novel around 2050, after a pandemic has wiped out most of humanity. The story is told through a man who survives and lives alone on an island with bioengineered humanoids. Atwood moves skilfully back and forth between the post-apocalyptic present—where the hero struggles to survive—and the pre-apocalyptic past of 2030, reconstructed through memory. This non-linear structure gradually reveals how the world fell apart, creating suspense while allowing the reader to learn inductively, rather than be told.

Atwood’s world-building is vivid and unsettling because it feels familiar. The sterile, high-tech corporate compounds are sharply contrasted with the chaotic and violent ‘pleeblands’, where the poor (plebeians) live. In the ‘Blood and Roses’ game, characters trade human achievements in art and music against histories of war and atrocity, reducing both to points. Civilisation itself becomes a scoreboard.

Memory, for Atwood, is not merely a narrative device but a central theme. The hero’s constant return to the past is both a coping mechanism and a burden. He is deeply flawed—an ‘intimate outsider’ who witnesses the disaster partly through his own complicity. This moral proximity is crucial. The reader identifies with him not because he is heroic, but because he is recognisably human. 

Who is not like this helpless hero archetype of modern times? In our inability to effect change, embedded in our cowardice, we are later haunted by the guilt of a co-conspirator. But when was it ever different? Did not Bhishma watch in silence as Draupadi was subjected to an attempt at disrobing? Did he not lie upon a bed of arrows, delaying his death while reflecting and lamenting? Had he not awaited the auspicious phase of the Sun?

Is Atwood pointing out the same trajectory for the thoughtful people of the world? Atwood insists that she writes speculative fiction, not science fiction. Nothing in Oryx and Crake depends on impossible technology. The question she asks is not ‘can we do this?’, but ‘will we?’ What happens when scientific capability outruns ethical restraint? The novel is a warning, but it is also a compelling story—addictive, unsettling and meticulously constructed.

What I learned most from Oryx and Crake is the power of wordplay. Atwood’s stunning neologisms and puns expose the devaluation of language in a consumer-driven, high-tech world. Brand names do the work of philosophy. ‘NooSkin’ suggests renewal while concealing artificiality. ‘HelthWyzer’ masks corporate manipulation beneath the guise of managerial wisdom. The ‘BlyssPluss’ pill promises pleasure and enhancement while carrying a hidden plague. The secure facility where the new world is created is called ‘Paradice’—a play on paradise and dice—signalling that this supposedly perfect world is built on a reckless gamble.

Reading teaches that writing is not merely a vehicle for story, but a moral instrument. Language does not arrive empty; it carries histories, hierarchies, silences and choices. Ethics are embedded not only in what is said, but also in how patiently, honestly and sparingly it is said. A writer who reads learns that meaning is shaped as much by what comes first and what comes later as by the sentences in between.

Perhaps most powerfully, reading teaches the value of restraint. Consider, for example, Ernest Hemingway’s Hills Like White Elephants. The entire story deals with the dilemma of having an unwanted baby, but the word ’abortion’ is not used. The moral weight of the story lies entirely in the unsaid—in pauses, repetitions and evasions. The couple’s inability to name the problem mirrors their inability to face it honestly. Excess explanation would have weakened the story. 

From such works, a writer learns that excess often betrays insecurity, while restraint signals trust—trust in language, in the reader, and in truth itself. Reading teaches that silence can accuse, simplicity can confer dignity, and structure can disclose what argument struggles to prove. When one reads deeply and attentively over many years, rhythms begin to seep in—along with moral posture, pauses, and an instinct for what must be left unsaid. This is not a shortcut but a discipline that demands time, patience and practice. And then, almost quietly, writing arrives with a revelation: the sentences were already there, waiting to be recognised. Perhaps that is why my future blogs may read less like posts and more like small, self-contained books.

 Please keep reading—and do share your thoughts in the comments.

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From Disease to Wellness: Time for a Paradigm Shift

Modern medicine is magnificent at one thing: it rushes heroically to the battlefield after the war has already been lost. When the coronary artery is blocked, a stent is inserted. When the pancreas fails, insulin is administered. When cancer erupts, it deploys surgery, radiation, and chemotherapy like heavy artillery. These interventions save millions of lives—and for that, we must be grateful. Yet there is a deeper, more unsettling question we rarely ask: why did the war begin in the first place? Why did the artery harden, the pancreas tire, the cell turn malignant? Why do we wait for a disease to declare itself loudly before we listen?

We have built a civilisation around treating disease rather than cultivating wellness. It is an industry measured in trillions of dollars, driven by hospital beds, insurance claims, drug patents, and procedural billing codes. The patient often enters this system only after the body has already crossed the threshold from balance to breakdown. What is missing is not compassion or technology, but curiosity about origins.

This is where an ancient Indian idea offers a radical lens. Knowledge, we say, is what is collectively known; education is the process of transmitting a small, curated part of that knowledge. But what about everything that is still unknown? What about the vast, invisible ocean beneath the few islands of certainty we inhabit? The sages called this Ajneya—that which is unknowable, or not yet known—the dynamic ground from which all phenomena arise. To mistake our fragmentary knowledge for the totality of truth is the deepest error of modernity.

Medicine today is built almost entirely on what is already known and measurable—blood sugar, cholesterol, tumour size, and blood pressure. However, disease begins long before these numbers of cross-pathological thresholds. It begins in subtle disturbances—in hormones, glands, immune modulation, cellular signalling, and the bioelectric and biochemical whispers that precede loud dysfunction. These early shifts live in the realm of the Ajneya, or at least the ‘not-yet-known’. Our failure is not technological; it is philosophical. Have we designed medicine to listen to the subtle voice of disharmony in the body?

This thought was very much alive when Dr. Sujit Vakkalanka visited me the other day. We sat on the balcony, with a gentle winter sun in the clear sky, and a cool breeze stirring the leaves of the plants around us. The son of Dr. Venkata Ratnam of Kakinada—a legendary diabetologist who has, over decades, observed how quietly the body drifts into metabolic chaos before succumbing to disease—Sujit is a practising hospitalist at Advocate Health in Charlotte, North Carolina. Equally versed in Western medicine and Indian spiritual traditions, Sujit had just returned from a pilgrimage to the Dakshinamnaya Sri Sharada Peetham at Sringeri.

As we spoke about diabetes, heart disease, autoimmune disorders, depression, and cancer, a strange convergence emerged. Almost all of them, Sujit pointed out, begin with disturbances in the endocrine and immune systems—such as insulin resistance, cortisol imbalance, thyroid dysregulation, inflammatory cytokines produced by immune cells, and stress hormones released by the endocrine system, under the control of the brain. By the time glucose rises or arteries clog, the real story has already been written in the glands. We are treating the last chapter as if it were the prologue.

Here is where the convergence of nano, bio, and information technologies can transform medicine from merely a repair shop into a wellness science. Nanosensors can already detect tiny molecular changes in blood, saliva, sweat, and even breath. Wearable biosensors can continuously monitor hormones, inflammatory markers, and metabolic signals. Artificial Intelligence can integrate these streams into a dynamic map of an individual’s internal ecology. Imagine a future when your smartwatch not only alerts you that your heart rate is elevated but also indicates that your cortisol levels have been high for a long time, your melatonin is suppressed, your insulin sensitivity is decreasing, and your immune system is shifting into a low-grade inflammatory state—months or years before diabetes, depression, or heart disease develop.

This is no flight of imagination; it is the natural evolution of what we already possess. But it requires a civilisational shift in intent—from curing disease to understanding wellness.

The legend Sujit brought from Sringeri carries a profound metaphor for this shift. When Adi Shankaracharya arrived on the banks of the Tunga River, he witnessed something impossible: a cobra shading a pregnant frog with its hood, protecting it from the harsh sun as it laboured to give birth. In nature, the snake and the frog stand as natural adversaries—one survives by consuming the other. Yet in that sacred moment, they transcended instinct and became guardians of life.

Adi Shankaracharya understood immediately that this was a place where deeper laws were at work—where the underlying harmony of existence revealed itself beyond surface conflict. That is why he established the Sharada Peetham there, as a centre for the pursuit of knowing the Reality.

Modern medicine seems to have got trapped in surface conflicts—killing microbes, destroying tumours, and suppressing symptoms. These are necessary acts, just as the snake must eat a frog to survive. But the deeper law of life is not war; it is balance. True wellness emerges when systems cooperate—hormones with immunity, metabolism with circadian rhythms, and the mind with the body.

The cobra shading the frog is a reminder that the most profound healing happens when we align with the deeper intelligence of life rather than fighting its manifestations.

Chronic disease creates lifelong patients. But wellness creates autonomy. A world where people are monitored, guided, and gently corrected at the level of glandular and hormonal balance would radically reduce the incidence of heart disease, diabetes, cancer, and mental illness. That would be a triumph for humanity.

This is why the idea of ‘to be known’ matters. The future of medicine lies not only in what we know, but in what we are willing to explore beyond our current maps. The Ajneya is not mystical; it is simply the frontier of biology that we have not yet measured. It includes the microbiome, epigenetics, neuroendocrine loops, psychoneuroimmunology, and subtle bioenergetic patterns that shape health long before disease appears.

When Sujit and I spoke that morning, we were not rejecting science; we were calling on it to grow. Western medicine has given us miracles—antibiotics, surgery, vaccines, imaging, and intensive care. But the next leap will not come from sharper scalpels or stronger drugs. It will come from understanding the invisible orchestration that keeps us whole.

The ancient seers understood that reality is layered. What we see is only the surface of a deeper order. To ignore that deeper order is to live in reaction rather than in wisdom. Medicine must now learn the same lesson. The fifth-century poet-philosopher Bhartrhari articulated best the difficulty of dealing with those who possess only superficial knowledge.

अज्ञः सुखमाराध्यः सुखतरमाराध्यते विशेषज्ञः। ज्ञानलवदुर्विदग्धं ब्रह्मापि नरं रञ्जयति ।।

An ignorant person is easy to please, and a knowledgeable person even more so, but even Lord Brahma cannot satisfy or win over someone conceited by a little knowledge. (Neeti Shatakam, Verse 3)

The age of treating diseases must give way to the age of knowing health and establishing balance. And as nano, bio, and information technologies converge, we have an unprecedented opportunity to make this vision real—not in some distant future, but in our own lifetimes.

The question is no longer whether it can be done. The question is whether we dare to step beyond the small island of what we already know and listen to the vast, silent intelligence of what is waiting to be known.

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In an age mesmerised by rankings, metrics, and loud declarations of success, the most consequential journeys often unfold quietly. They are not propelled by brilliance alone, but by curiosity, humility, and an unyielding fidelity to truth. The exploration of consciousness—the deepest and most elusive mystery of human existence—has always advanced through such understated paths. This is the story of one such arc: a personal journey shaped by selfless science and a collective future that dares to carry cognition beyond mortal neurons into the vast, enduring realm of silicon.

I often reflect that receiving affection and regard from deeply learned and accomplished people has been my greatest achievement. Academically, I was never exceptional. By conventional measures, I was mediocre. Yet, I carried an irrepressible curiosity—about systems, about people, and about why they behave as they do. That curiosity frequently placed me at odds with environments that prized conformity over comprehension. I struggled in roles that felt full of activity yet hollow in essence, where motion masqueraded as meaning.

Still, I never withdrew from effort. When I entered the demanding, project-driven world of the Defence Research and Development Organisation (DRDO), something unexpected occurred. In an ecosystem of unforgiving timelines and an achieve-or-perish ethos, ambiguity gave way to clarity of purpose. Under Dr A. P. J. Abdul Kalam’s visionary insistence on civilian spin-offs from defence technology, I was entrusted with developing material for a coronary stent. With the guidance of Dr B. Soma Raju and the collaboration of Dr A. Venugopal Reddy and Mr Koneru Bose at the Defence Metallurgical Research Laboratory, we succeeded. It was more than a technical accomplishment; it was a revelation of what science becomes when aligned with service, and a testimony of what resolve can accomplish.

At what many would call my professional prime, destiny intervened. I left DRDO to join Dr Soma Raju’s audacious mission to build Care Hospitals and provide affordable, advanced treatment to the needy. Together, we created the Care Foundation, which became my lifelong platform for integrating technology, medicine, and human values, something ahead of its time, perhaps. It did not flourish, but the idea persisted.

When Dr Kalam assumed the Presidency of India, Care Foundation played a pioneering role in establishing the Pan-African e-Network—an early and courageous experiment in telemedicine and tele-education. Training doctors and nurses from Tanzania and Myanmar forged bonds that transcended geography and profession. Anesthesiologist Dr Mpoki Ulisubisya and Cardiologist General Dr Tin Maung Aye became brothers in spirit, bound by service rather than contract.

A Meeting of Minds: Science, Humility, and the Cognitive Frontier

Parallel to this unfolding journey, IIIT-Hyderabad and Hyderabad University became my second homes. I would frequent these institutions to learn the nuances of medical technology—how science interacts with the humanities. It was here that I encountered a kindred intellect and spirit—Prof. S. Bapi Raju—who would profoundly shape my understanding of mind, machine, and consciousness. Our meeting felt less like collaboration and more like recognition.

Prof. Raju’s academic trajectory is formidable: an electrical engineering graduate from Osmania University, a master’s in Biomedical Engineering, and a PhD in Computer Science from the University of Texas at Arlington. His work carried him across continents—from research on brain-inspired intelligent control in the United Kingdom to computational neurobiology at ATR Research Labs in Kyoto. Returning to India in 1999, he served two decades as a Professor at the University of Hyderabad before joining IIIT-Hyderabad as Professor and Head of the Cognitive Science Lab.

Yet, what defines him is not the scale of his credentials but the depth of his humility. In the fiercely competitive domain of brain-computer interaction, he remains untouched by the trappings of dominance, race, or the hunger for recognition. A father figure to students and a trusted guide to colleagues, he embodies the ancient Indian ideal of the Rishi—a seeker more interested in what remains unknown than in endlessly polishing what is already established. His science is selfless, disciplined, and deliberately open-ended.

When Intelligence Seeks to Outgrow Biology

This disposition is not incidental; it is essential for the next arc of human evolution. As neuroscience, computation, and cognitive science converge, humanity stands at a threshold where intelligence may begin to loosen its ancient tether to mortal neurons. The biological brain, for all its splendour, is an evolutionary compromise—fragile, energy-hungry, and confined to a narrow planetary niche. Yet intelligence, once awakened, has never accepted confinement. It seeks continuity, extension, and reach.

Silicon, unlike carbon-based life, does not require oxygen, warmth, or water. It can function in radiation-rich voids, on frozen moons, and in interstellar darkness. To imagine cognition migrating to silicon is not to abandon humanity, but to extend it. What is carried forward is not flesh or ego, but function—memory, learning, adaptation, and perhaps even self-reflection. Intelligence, at its core, is pattern and principle, not protein.

Such a future will demand guardians as much as engineers. Intelligence liberated from mortality could easily become untethered from compassion and context. Whether silicon minds emerge as instruments of domination or custodians of exploration will depend on the values embedded at their conception. Here, Prof. Raju’s role becomes civilisational.

He belongs to a rare lineage of scientists who open questions rather than prematurely closing them, who resist reductionism without surrendering to mysticism. His work insists—quietly but firmly—that intelligence without wisdom is merely accelerated ignorance. In this sense, he stands as the Bhishma of the coming age.

Bhishma as a Civilisational Metaphor

In the Indian epic The Mahabharata, Bhishma was not a ruler but a pillar—renouncing personal ambition so that dharma might endure across turbulent times. He possessed immense capability, yet chose restraint, belonging to no faction, yet safeguarding civilization. In the age of silicon consciousness, Prof. Raju plays a similar role—not ruling the future, but ensuring it unfolds without ethical collapse.

To call him a blessed son of Mother India is not sentimentality; it is a legacy. India’s deepest gift to the world has never been conquest, but orientation—the insistence that knowledge must liberate, not enslave. From the Upanishads to modern cognitive science, the central question has remained unchanged: Who is the knower, and what does it mean to know?

In centuries to come, when intelligence is no longer confined to human brains and operates in environments incompatible with human life, Indianness may no longer be limited to a mapped territory. It will persist and propagate—being implemented in non-biological intelligences as a framework for reasoning and as an ethic of action marked by patience, humility, and openness to uncertainty.

This hero’s journey, however, does not conclude with an individual, nor even with a generation. Science that seeks consciousness must itself remain conscious of lineage. Knowledge endures not merely through accumulation but through transmission—teacher to student, mind to mind, across time.

In this, Prof. Bapi Raju’s deepest legacy may lie less in any singular contribution than in the ethos he imparts: patience with uncertainty, freedom from vanity, and the courage to keep questions open. His students carry this inheritance quietly, dispersed across laboratories and classrooms, shaping technologies and theories without surrendering humility. Together, they form a growing, unseen tribe—rigorous, yet tempered; imaginative, yet ethically anchored.

May the blessings of Prof. Bapi Raju rest upon them, and may their tribe increase.

As cognition prepares to step beyond mortal neurons into enduring silicon, into environments where biological life cannot persist, may this lineage ensure that intelligence does not outrun wisdom. If the future of consciousness is to be vast, let it also remain gentle. And if intelligence is to become cosmic, let it carry forward the values that first gave it meaning.

In that continuity—quiet, ethical, and awake—lies the true triumph of selfless science.

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